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Dr. rer. nat Markus Plaumann

Dr. rer. nat. Markus Plaumann

Medizinische Fakultät
Institut für Biometrie und Medizinische Informatik (IBMI)
Haus 2, Leipziger Str. 44, 39120, Magdeburg, H2/213
Vita
2001-2006 Chemiestudium an der Universität Bremen
12/2006 Diplom in Chemie; Diplomarbeit: "Synthese und Charakterisierung lipophiler fluorierter Gd-Kontrastmittel für die molekulare 1H- und 19F-Bildgebung", Universität Bremen, Institut für Organische Chemie, Arbeitsgruppe Instrumentelle Analytik, Prof. Leibfritz
2007-2010 Doktorand: "Synthese und Charakterisierung paramagnetischer Kontrastmittel für die molekulare Bildgebung", Universität Bremen, Arbeitsgruppe von Prof. Dr. D. Leibfritz.
2007-2010 Dozent für Biochemie in der MTA-Schule, Bremen/Bremerhaven
2008-2010 Dozent für Chemie in der MTA-Schule, Bremen/Bremerhaven
04/2010-03/2011 Wissenschaftlicher Mitarbeiter an der Universität Bremen im Institut für Organische Chemie bei Prof. Dr. D. Leibfritz.
seit 01/2011 Wissenschaftlicher Mitarbeiter (Post-Doc) an der Otto-von-Guericke-Universität Magdeburg im Institut für Biometrie und Medizinische Informatik bei Prof. Dr. Dr. J. Bernarding. Forschungsbereich: Hyperpolarisation, 19F-MR-Bildgebung.
Projekte
Abgeschlossene Projekte Steigerung der MR-Sensitivität von 19F Biomarkern und PET-analogen 19F-markierten Rezeptorliganden durch Parawasserstoff-induzierte Polarisation Laufzeit: 01.08.2014 - 31.07.2017
Kooperationen
  • Dr. Jonas Warneke, Perdue University, Department of Chemistry, West Lafayette, IN, USA
  • Prof. Dr. Andreas Dotzauer, Universität Bremen, Laboratorium für Virusforschung
  • Dr. Sven Gottschalk, Institute for Biological and Medical Imaging (IBMI), Helmholtz Zentrum München
  • Dr. Vladimir A. Azov, University of the Free State, Department of Chemistry, Bloemfontein, South Africa
  • Prof. Dr. Gerd Buntkowsky, TU Darmstadt, Physikalische Chemie
Publikationen

2018

Abstrakt
Bruns, Christian;  Plaumann, Markus;  Herrmann, Tim;  Euchner, Frederike;  Kumar, Suchit;  Jo, Youngseung;  Ringleb, Rainer;  Lee, Chulhyun;  Oh, Chang-Hyun;  Bernarding, Johannes 

Temperatursensitive 19F-markierte Moleküle für die 19F-Bildgebung in einem 7 T Ganzkörper MRT-System
In: 49. Jahrestagung der Deutschen Gesellschaft für Medizinische Physik (DGMP) e. V. und 21. Jahrestagung der Deutschen Sektion der International Society for Magnetic Resonance in Medicine (ISMRM) e.V.: 19. - 22. September 2018, Meistersingerhalle, Münchener Strasse 21, 90478 Nürnberg - [Berlin]: [Deutsche Gesellschaft für Medizinische Physik e.V.], 2018, P 20, Seite 282; https://www.dgmp-kongress.de/

Buckenmaier, Kai;  Rudolph, Matthias;  Fehling, Paul;  Back, Christoph;  Bernarding, Johannes;  Kölle, Dieter;  Kleiner, Reinhold;  Scheffler, Klaus;  Plaumann, Markus 

SQUID based magnetic resonance imaging for the investigation of in situ and in vivo hyperpolarization techniques
In: European Molecular Imaging Meeting - EMIM 2018, March 20 - 23, 2018, Kursaal San Sebastián, Spain: 13th annual meeting of ESMI, 2018, PS-13-2, insges. 1 Seite; http://www.eventclass.org/contxt_emim2018/online-program/session?s=PS-13

Euchner, Frederike;  Bruns, Christian;  Ringleb, Rainer;  Bargon, Joachim;  Plaumann, Markus;  Bernarding, Johannes 

Comparison of the hyperpolarization of different fluorinated aromatic systems via photo-CIDNP
In: An International Conference on Nuclear Hyperpolarization: Sep 2-5 2018, HYP 18, 2018, P 49, Seite 112; https://generic.wordpress.soton.ac.uk/hyp18/abstracts/

Euchner, Frederike;  Bruns, Christian;  Ringleb, Rainer;  Müller, Darius;  Bommerich, Ute;  Herrmann, Tim;  Plaumann, Markus;  Bernarding, Johannes 

Construction of an flow-phantom for MRI based on MR imaging data of a rats head
In: European Molecular Imaging Meeting - EMIM 2018, March 20 - 23, 2018, Kursaal San Sebastián, Spain: 13th annual meeting of ESMI, 2018, #268, insges. 1 Seite; http://www.eventclass.org/contxt_emim2018/online-program/session?s=PO-02

Euchner, Frederike;  Bruns, Christian;  Ringleb, Rainer;  Bargon, Joachim;  Bernarding, Johannes;  Plaumann, Markus 

LED-based photo-CIDNP increases 19F signal for MRI
In: 40th FGMR Discussion Meeting: Leipzig, Germany, September 10-13, 2018 - Leipzig, Germany: University of Leipzig, 2018, Poster 93, Seite 215

Herrmann, Tim;  Bruns, Christian;  Lützkendorf, Ralf;  Euchner, Frederike;  Plaumann, Markus;  Bernarding, Johannes 

Big data showroom - ein Konzept für standortübergreifende Kooperationen
In: 63. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS): 02.09.-06.09.2018, Osnabrück - Düsseldorf: German Medical Science GMS Publishing House, 2018, DocAbstr. 175, insges. 2 Seiten; http://dx.doi.org/10.3205/18gmds128

Plaumann, Markus 

Boosting 19F MRI sensitivity by hyperpolarization
In: Joint annual meeting ISMRM-ESMRMB 2018: Paris Expo Porte de Versailles, Paris, France, 16-21 June 2018, SMRT 27th Annual Meeting, 2018, Session Number: MIS-10, insges. 1 Seite; https://www.ismrm.org/18/program_files/MIS10.htm

Plaumann, Markus 

Hyperpolarisation mittels Parawasserstoff (PHIP&SABRE)
In: 49. Jahrestagung der Deutschen Gesellschaft für Medizinische Physik (DGMP) e. V. und 21. Jahrestagung der Deutschen Sektion der International Society for Magnetic Resonance in Medicine (ISMRM) e.V.: 19. - 22. September 2018, Meistersingerhalle, Münchener Strasse 21, 90478 Nürnberg - [Berlin]: [Deutsche Gesellschaft für Medizinische Physik e.V.], S. 230; https://www.dgmp-kongress.de/

Plaumann, Markus;  Euchner, Frederike;  Ringleb, Rainer;  Hadjiali, Sara;  Bargon, Joachim;  Bommerich, Ute;  Buntkowsky, Gerd;  Bernarding, Johannes 

SABRE-based hyperpolarization and substituent effects
In: An International Conference on Nuclear Hyperpolarization: Sep 2-5 2018, HYP 18, 2018, P 104, Seite 167; https://generic.wordpress.soton.ac.uk/hyp18/abstracts/

Begutachteter Zeitschriftenartikel
Backenköhler, Jana;  Reck, Bernhard;  Plaumann, Markus;  Spiteller, Peter 

Total synthesis of mycenarubin A, sanguinolentaquinone and mycenaflavin B and their cytotoxic activities
In: European journal of organic chemistry - Weinheim: Wiley-VCH Verl, 22, S. 2806-2816, 2018; http://dx.doi.org/10.1002/ejoc.201800417

Bernarding, Johannes;  Euchner, Frederike;  Bruns, Christian;  Ringleb, Rainer;  Müller, Darius;  Trantzschel, Thomas;  Bargon, Joachim;  Bommerich, Ute;  Plaumann, Markus 

Low-cost LED-based Photo-CIDNP enables biocompatible hyperpolarization of 19 F for NMR and MRI at 7 T and 4.7 T
In: ChemPhysChem: a European journal of physical chemistry and chemical physics - Weinheim: Wiley-VCH Verl, Bd. 19.2018, 19, S. 2453-2456; http://dx.doi.org/10.1002/cphc.201800570

Buckenmaier, Kai;  Rudolph, Matthias;  Fehling, Paul;  Steffen, Theodor;  Back, Christoph;  Bernard, Rebekka;  Pohmann, Rolf;  Bernarding, Johannes;  Kleiner, Reinhold;  Kölle, Dieter;  Plaumann, Markus;  Scheffler, Klaus 

Mutual benefit achieved by combining ultralow-field magnetic resonance and hyperpolarizing techniques
In: Review of scientific instruments: a monthly journal devoted to scientific instruments, apparatus, and techniques - [S.l.]: American Institute of Physics, Bd. 89 (2018), 12, Art.-Nr. 125103, insges. 12 S.; http://dx.doi.org/10.1063/1.5043369

Herrmann, Tim;  Liebig, Thorsten;  Mallow, Johannes;  Bruns, Christian;  Stadler, Jörg;  Mylius, Judith;  Brosch, Michael;  Svedja, Jan Taro;  Chen, Zhichao;  Rennings, Andreas;  Scheich, Henning;  Plaumann, Markus;  Hauser, Marcus;  Bernarding, Johannes;  Erni, Daniel Gregor 

Metamaterial-based transmit and receive system for whole-body magnetic resonance imaging at ultra-high magnetic fields
In: PLOS ONE - San Francisco, California, US: PLOS, Bd. 13.2018, 1, Art.-Nr. e0191719, insges. 17 S.; http://dx.doi.org/10.1371/journal.pone.0191719

Hövener, Jan-Bernd;  Pravdivtsev, Andrey N.;  Kidd, Bryce;  Bowers, Russell;  Glöggler, Stefan;  Kovtunov, Kirill V.;  Plaumann, Markus;  Katz-Brull, Rachel;  Buckenmaier, Kai;  Jerschow, Alexej;  Reineri, Francesca;  Theis, Thomas;  Shchepin, Roman V.;  Wagner, Shawn;  Bhattacharya, Pratip;  Zacharias, Niki M.;  Chekmenev, Eduard Y. 

Parahydrogenbased hyperpolarization for biomedicine
In: Angewandte Chemie / International edition - Weinheim: Wiley-VCH, Bd. 57.2018, 35, S. 11140-11162; http://dx.doi.org/10.1002/anie.201711842

Hövener, Jan-Bernd;  Pravdivtsev, Andrey N.;  Kidd, Bryce;  Bowers, C. Russell;  Glöggler, Stefan;  Kovtunov, Kirill V.;  Plaumann, Markus;  Katz-Brull, Rachel;  Buckenmaier, Kai;  Jerschow, Alexej;  Reineri, Francesca;  Theis, Thomas;  Shchepin, Roman V.;  Wagner, Shawn;  Bhattacharya, Pratip;  Zacharias, Niki M.;  Chekmenev, Eduard Y. 

Parawasserstoff-basierte Hyperpolarisierung für die Biomedizin
In: Angewandte Chemie - Weinheim: Wiley-VCH, Bd. 130.2018, 35, S. 11310-11333; http://dx.doi.org/10.1002/ange.201711842

Skinner, Jason Graham;  Menichetti, Luca;  Flori, Alessandra;  Dost, Anna;  Schmidt, Andreas Benjamin;  Plaumann, Markus;  Gallagher, Ferdia Aiden;  Hövener, Jan-Bernd 

Metabolic and molecular imaging with hyperpolarised tracers
In: Molecular imaging & biology: MIB : the official journal of the Academy of Molecular Imaging - Amsterdam [u.a.]: Elsevier Science, Bd. 20.2018, 6, S. 902-918; http://dx.doi.org/10.1007/s11307-018-1265-0

2017

Abstrakt
Backenköhler, Jana;  Reck, Bernhard;  Plaumann, Markus;  Spiteller, Peter 

Total synthesis of mycenaflavin B and mycenarubin A
In: ESOC 2017 - [Köln, Germany]: [Universität zu Köln, Institut für Organische Chemie], insges. 1 S.; http://www.esoc.uni-koeln.de/

Bruns, Christian;  Ringleb, Rainer;  Euchner, Frederike;  Bommerich, Ute;  Herrmann, Tim;  Bernarding, Johannes;  Plaumann, Markus 

Fluorinated molecules enable temperature determination in MRS and MRI
In: European Molecular Imaging Meeting, EMIM 2017, April 5 - 7 2017: 12th annual meeting of the ESMI, 2017, PW 02/21, insges. 1 S.; http://esmi-insight.eu/emim2017/contxt/programme/default_session.asp?node=&day=thursday&sessionID=19#session_42

Bruns, Christian;  Plaumann, Markus;  Herrmann, Tim;  Euchner, Frederike;  Ringleb, Rainer;  Oh, Chang-Hyun;  Lee, Chulhyun;  Jo, Youngseung;  Kumar, Suchit;  Bernarding, Johannes 

Temperature determination using 19F-substituted molecules
In: ICMRI 2017: the 5th International Congress on Magnetic resonance imaging & 22nd Annual Scientific Meeting of KSMRM : innovative discovery through MRI, March 23 - 25, 2017, Grand Hilton Hotel Seoul, Korea, 2017, SS10-07, insges. 1 S.

Bruns, Christian;  Ringleb, Rainer;  Euchner, Frederike;  Herrmann, Tim;  Bommerich, Ute;  Bernarding, Johannes;  Plaumann, Markus 

Temperature determination via 19F MRS and MRI
In: 39th FGMR Annual Discussion Meeting: Joint Conference of the French and German Magnetic Resonance Societies$dBayreuth, Germany, September 25 - 28, 2017, S. 54

Bruns, Christian;  Herrmann, Tim;  Plaumann, Markus;  Oh, Chang-Hyun;  Lee, Chulhyun;  Kumar, Suchit;  Bernarding, Johannes 

Unified proton and fluorine imaging of small and low spin density samples at a human whole-body 7 T MRI
In: ISMRM 25th annual ISMRM meeting & exhibition, 22 - 27 April 2017: SMRT annual meeting, 22 - 24. April 2017, Honolulu, HI, USA, 2017, Abs. 4405, insges. 2 S.; http://dev.ismrm.org/2017/4405.html

Bruns, Christian;  Plaumann, Markus;  Herrmann, Tim;  Euchner, Frederike;  Ringleb, Rainer;  Jo, Youngseung;  Kumar, Suchit;  Lee, Chulhyun;  Oh, Chang-Hyun;  Bernarding, Johannes 

19F-imaging using temperature sensitive 19F-substituted molecules in a 7 T whole-body MRI system
In: Magnetic resonance materials in physics, biology and medicine: MAGMA : the official journal of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB) - Berlin: Springer, Bd. 30.2017, Suppl. 1, Abstract 423, Seite S404-S405; https://link.springer.com/article/10.1007/s10334-017-0634-z

Bruns, Christian;  Plaumann, Markus;  Herrmann, Tim;  Euchner, Frederike;  Ringleb, Rainer;  Kumar, Suchit;  Jo, Youngseung;  Lee, Chulhyun;  Oh, Chang-Hyun;  Bernarding, Johannes 

19F-substituted molecules for temperature sensitive 19F-imaging in a 7 T whole-body MRI system
In: Red hot MRI: fluorine imaging: an informal symposium to discuss and foster collaborative 19F MRI : Berlin 15.+ 16. 10.2017, S. 24; http://www.schlaganfallcentrum.de/fileadmin/redaktion/csb/02_Veranstaltungen/redhotMRI_flyer_web.pdf

Buckenmaier, Kai;  Rudolph, Matthias;  Back, Christoph;  Engelmann, Joern;  Rudin, Juri;  Misztal, Tomasz;  Bommerich, Ute;  Scheffler, Klaus;  Koelle, Dieter;  Kleiner, Reinhold;  Mayer, Hermann A.;  Bernarding, Johannes;  Plaumann, Markus 

SQUID-based ultralow field nuclear magnetic resonance spectroscopy using the para-H2 based hyperpolarization technique SABRE
In: ISMRM 25th annual ISMRM meeting & exhibition, 22 - 27 April 2017: SMRT annual meeting, 22 - 24. April 2017, Honolulu, HI, USA, 2017, Abstract 3033, insges. 2 S.; http://dev.ismrm.org/2017/3033.html

Euchner, Frederike;  Bommerich, Ute;  Ringleb, Rainer;  Bargon, Joachim;  Plaumann, Markus;  Bernarding, Johannes 

Hyperpolarization of two tyrosine derivatives using photo-CIDNP
In: European Molecular Imaging Meeting, EMIM 2017, April 5 - 7 2017: 12th annual meeting of the ESMI, 2017, PW16/164, insges. 1 S.; http://esmi-insight.eu/emim2017/contxt/programme/default_session.asp?node=34&day=&sessionID=56&bySearch=true&search=hyperpolarization+of#318

Euchner, Frederike;  Trantzschel, Thomas;  Bommerich, Ute;  Ringleb, Rainer;  Bargon, Joachim;  Bernarding, Johannes;  Plaumann, Markus 

LED induced 13C MR signal enhancements in aqueous solution at 7T
In: Magnetic resonance materials in physics, biology and medicine: MAGMA : the official journal of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB) - Berlin: Springer, Bd. 30.2017, Suppl. 1, Abstract 428, Seite S408-S409; https://link.springer.com/article/10.1007/s10334-017-0634-z

Euchner, Frederike;  Plaumann, Markus;  Trantzschel, Thomas;  Bargon, Joachim;  Bommerich, Ute;  Bernarding, Johannes 

photo-CIDNP for 19F MR amino acid-protein interaction studies in physiological solvents
In: ISMRM 25th annual ISMRM meeting & exhibition, 22 - 27 April 2017: SMRT annual meeting, 22 - 24. April 2017, Honolulu, HI, USA, 2017, Abstract 3036, insges. 2 S.; http://dev.ismrm.org/2017/3036.html

Müller, Darius;  Euchner, Frederike;  Ringleb, Rainer;  Bommerich, Ute;  Bargon, Joachim;  Buntkowski, Gerd;  Bernarding, Johannes;  Plaumann, Markus 

Positive charged nitrogen atom influences polarization transfer in PHIP experiments
In: 39th FGMR Annual Discussion Meeting: Joint Conference of the French and German Magnetic Resonance Societies$dBayreuth, Germany, September 25 - 28, 2017, 2017, Poster 109, S. 211

Plaumann, Markus;  Euchner, Frederike;  Ringleb, Rainer;  Hadjiali, Sara;  Bargon, Joachim;  Buntkowsky, Gerd;  Bernarding, Johannes;  Bommerich, Ute 

Examination of the hyperpolarizability of fluorinated nicotinic acids and further pyridine carboxylic acids using SABRE
In: ISMRM 25th annual ISMRM meeting & exhibition, 22 - 27 April 2017: SMRT annual meeting, 22 - 24. April 2017, Honolulu, HI, USA, 2017, Abstract 3038, insges. 2 S.; http://dev.ismrm.org/2017/3038.html

Plaumann, Markus;  Buckenmaier, Kai;  Hadjiali, Sara;  Euchner, Frederike;  Rudolph, Matthias;  Ringleb, Rainer;  Bommerich, Ute;  Bargon, Joachim;  Buntkowsky, Gerd;  Scheffler, Klaus;  Bernarding, Johannes 

Signal detection of 19F hyperpolarized pyridine derivatives at low and at high magnetic field strengths
In: Red hot MRI: fluorine imaging: an informal symposium to discuss and foster collaborative 19F MRI : Berlin 15.+ 16. 10.2017, S. 25; http://www.schlaganfallcentrum.de/fileadmin/redaktion/csb/02_Veranstaltungen/redhotMRI_flyer_web.pdf

Plaumann, Markus;  Ringleb, Rainer;  Euchner, Frederike;  Hadjiali, Sara;  Bargon, Joachim;  Bommerich, Ute;  Buntkowsky, Gerd;  Bernarding, Johannes 

1H, 13C and 19F hyperpolarization of three substituted pyridine derivates
In: Magnetic resonance materials in physics, biology and medicine: MAGMA : the official journal of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB) - Berlin: Springer, Bd. 30.2017, Suppl. 1, Abstract 675, Seite S634-S635; https://link.springer.com/article/10.1007%2Fs10334-017-0635-y

Begutachteter Zeitschriftenartikel
Buckenmaier, Kai;  Rudolph, Matthias;  Back, Christoph;  Misztal, Tomasz;  Bommerich, Ute;  Fehling, Paul;  Koelle, Dieter;  Kleiner, Reinhold;  Mayer, Hermann A.;  Scheffler, Klaus;  Bernarding, Johannes;  Plaumann, Markus 

SQUID-based detection of ultra-low-field multinuclear NMR of substances hyperpolarized using signal amplification by reversible exchange
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, Bd. 7.2017, Art.-Nr. 13431, insges. 9 S.; http://dx.doi.org/10.1038/s41598-017-13757-7

2016

Abstrakt
Azov, Vladimir A.;  Warneke, Jonas;  Plaumann, Markus 

Gas-phase binding study of dodecaborate dianions and receptors with hydrophobic binding pockets
In: MSCEC, Münster, 2016

Bruns, Christian;  Herrmann, Tim;  Oh, Chang-Hyun;  Plaumann, Markus;  Lee, Chulhyun;  Jo, Youngseung;  Mallow, Johannes;  Park, Joshua;  Kumar, Suchit;  Bernarding, Johannes 

Decoupling of an 8-channel monopole head coil at 7 tesla
In: ICMRI 2016: the 4th International Congress on MRI & 21st Annual Scientific Meeting of KSMRM, March 24 - 26, 2016, Grand Hilton Hotel Seoul, Korea, (2016), insges. 1 S.

Bruns, Christian;  Herrmann, Tim;  Oh, Chang-Hyun;  Kumar, Suchit;  Plaumann, Markus;  Lee, Chulhyun 

Transmit-/receive system for hi-res micro imaging with 19F contrast agent at 7 T UHF MRI
In: ESMRMB 2016, 33rd Annual Scientific Meeting, Vienna/AT Sept. 29 - Oct. 1 : meeting guide, 2016, Abs. NEWS 9, Seite 115

Euchner, Frederike;  Ringleb, Rainer;  Bargon, Joachim;  Bommerich, Ute;  Bernarding, Johannes;  Plaumann, Markus 

First hyperpolarization of quaternary pyridinium salts using PHIP
In: Proc. Intl. Soc. Mag. Reson. Med., 2016, 3688

Euchner, Frederike;  Bommerich, Ute;  Trantzschel, Thomas;  Bargon, Joachim;  Plaumann, Markus;  Bernarding, Johannes 

LED induced 19F hyperpolarization in physiological solvent
In: Magnetic resonance materials in physics, biology and medicine : MAGMA : the official journal of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB). - Berlin : Springer; Bd. 29 (2016), Suppl. 1, Abs. 155, Seite S148

Euchner, Frederike;  Bommerich, Ute;  Ringleb, Rainer;  Bargon, Joachim;  Bernarding, Johannes;  Plaumann, Markus 

PHIP of fluorinated quaternary pyridinium ions
In: European Molecular Imaging Meeting, EMIM 2016, 8-10 March: the EMIM 2016 was the 11th annual meeting of the ESMI, 2016, Abs. 92, insges. 1 S.

Herrmann, Tim;  Mallow, Johannes;  Bruns, Christian;  Plaumann, Markus;  Oh, Chang-Hyun;  Lee, Chulhyun;  Jo, Youngseung;  Park, Joshua;  Kumar, Suchit;  Bernarding, Johannes 

Improved application of BioEM field simulation software for new B1 transmit concepts at ultra-high field MRI
In: ICMRI 2016: the 4th International Congress on MRI & 21st Annual Scientific Meeting of KSMRM, March 24 - 26, 2016, Grand Hilton Hotel Seoul, Korea, 2016, Abs. SY14-2, insges. 2 S.

Plaumann, Markus;  Euchner, Frederike;  Ringleb, Rainer;  Hadjiali, Sara;  Bargon, Joachim;  Buntkowsky, Gerd;  Bernarding, Johannes;  Bommerich, Ute 

Hyperpolarization of fluorinated pyridine carboxylic acids
In: Magnetic resonance materials in physics, biology and medicine: MAGMA : the official journal of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB) - Berlin: Springer, Bd. 29.2016, Suppl. 1, Abs. 398, Seite S370

Plaumann, Markus 

Introduction into MRI and MPI technology and methods for molecular imaging
In: European Molecular Imaging Meeting, EMIM 2016, 8-10 March: the EMIM 2016 was the 11th annual meeting of the ESMI, 2016, Abs. 490, insges. 1 S.

Plaumann, Markus;  Trantzschel, Thomas;  Bargon. Joachim,;  Bommerich, Ute;  Bernarding, Johannes 

LED induced 19F MR signal enhancement at 7T
In: Proc. Intl. Soc. Mag. Reson. Med. 2016, 3684

Plaumann, Markus;  Ringleb, Rainer;  Euchner, Frederike;  Bruns, Christian;  Munt, Maxim;  Herrmann, Tim;  Bommerich, Ute;  Bernarding, Johannes 

Temperature dependency of 19F chemical shifts in aqueous solution
In: 38th FGMR Discussion Meeting of the German Magnetic Resonace Society : Düsseldorf, Germany, September 12th to 15th, 2016; (2016), Abs. P20, Seite 100

Begutachteter Zeitschriftenartikel
Warneke, Jonas;  Jenne, Carsten;  Bernarding, Johannes;  Azov, Vladimir A.;  Plaumann, Markus 

Evidence for an intrinsic binding force between dodecaborate dianions and receptors with hydrophobic binding pockets
In: Chemical communications: ChemComm - Cambridge: Soc, Bd. 52.2016, 37, S. 6300-6303; http://dx.doi.org/10.1039/c6cc01233g

Buchbeitrag
Bommerich, Ute;  Bernarding, Johannes;  Lego, Denise;  Trantzschel, Thomas;  Plaumann, Markus 

Hyperpolarization for signal enhancement in fluorine MR applications
In: Fluorine Magnetic Resonance Imaging: Ulrich - Milton: Pan Stanford Publishing, S. 59-102, 2016; http://dx.doi.org/10.1201/9781315364605-4

2015

Abstrakt
Warneke, Jonas;  Azov, Vladimir A.;  Bernarding, Johannes;  Jenne, Carsten;  Plaumann, Markus 

Chemical masked dianion [B12F12]- enabled cell labeling
In: Magnetic resonance materials in physics, biology and medicine : (MAGMA) ; the official journal of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB). - Heidelberg : Springer; Bd. 28.2015, Suppl. 1, Abs. 46, S. S35-S36Publikationslink   

Artikel in Kongressband
Bommerich, Ute;  Trantzschel, Thomas;  Plaumann, Markus;  Lego, Denise;  Buntkowsky, Gerd;  Sauer, Grit;  Gutmann, Torsten;  Bargon, Joachim;  Bernarding, Johannes 

19F-Hyperpolarized Structures as Marker for the Improved Detection of Amyloid Plaques
In: Proc. Intl. Soc. Mag. Reson. Med. 2015, 1878

Plaumann, Markus;  Trantzschel, Thomas;  Lego, Denise;  Bargon, Joachim;  Bommerich, Ute;  Bernarding, Johannes 

LED basierte 19F-MR-Signalverstärkung bei 7T
In: Jahrestagung der Deutschen Sektion der ISMRM e.V. - Köln : Dt. Sektion der ISMRM; 18. Jahrestagung 19.-20.11.2015, Münster, V24, S. 116-117Publikationslink   

Plaumann, Markus;  Wüstemann, Jan;  Lego, Denise;  Trantzschel, Thomas;  Sauer, Grit;  Gutmann, Torsten;  Bargon, Joachim;  Buntkowsky, Gerd;  Bernarding, Johannes;  Bommerich, Ute 

Novel developments in the hyperpolarization of 19F using parahydrogen
In: Joint 5th International DNP Symposium and COST Action EuroHyperPol Final Meeting, Egmond aan Zee (Niederlande), 2015

Plaumann, Markus;  Wüstemann, Jan;  Lego, Denise;  Trantzschel, Thomas;  Sauer, Grit;  Gutmann, Torsten;  Buntkowsky, Gerd;  Bargon, Joachim;  Bernarding, Johannes;  Bommerich, Ute 

Parahydrogen Induced Polarization of fluorinated substrates for 19F MR spectroscopy and imaging
In: EMIM, Tübingen, 2015, 127

Plaumann, Markus;  Lego, Denise;  Trantzschel, Thomas;  Wüstemann, Jan;  Sauer, Grit;  Gutmann, Torsten;  Buntkowsky, Gerd;  Bargon, Joachim;  Bommerich, Ute;  Bernarding, Johannes 

Parahydrogen Induced Polarization (PHIP) of anticancer drug substructures
In: GDCh – FGMR, Darmstadt (Deutschland), 2015, #78

Plaumann, Markus;  Trantzschel, Thomas;  Wüstemann, Jan;  Lego, Denise;  Sauer, Grit;  Gutmann, Torsten;  Bargon, Joachim;  Buntkowsky, Gerd;  Bernarding, Johannes;  Bommerich, Ute 

PHIP hyperpolarization of linear and branched fluorinated alkanes as well as their interaction with cyclodextrins
In: Proc. Intl. Soc. Mag. Reson. Med. 2015, 1879

Plaumann, Markus;  Kemken, Dorit;  Dülcks, Thomas;  Leibfritz, Dieter 

Untersuchung der Fragmentierungen von auf Cyclen basierenden Ligandensystemen mittels ESI-MS/MS und MS³
In: DGMS, Wuppertal, 2015, PII17

Begutachteter Zeitschriftenartikel
Herrmann, Tim;  Mallow, Johannes;  Plaumann, Markus;  Luchtmann, Michael;  Stadler, Jörg;  Mylius, Judith;  Brosch, Michael;  Bernarding, Johannes 

The travelling-wave primate system - a new solution for magnetic resonance imaging of macaque monkeys at 7 Tesla ultra-high field
In: PLOS ONE - San Francisco, California, US: PLOS, Bd. 10.2015, 6, Art. e0129371, insges. 18 S.; http://dx.doi.org/10.1371/journal.pone.0129371

Warneke, Jonas;  Plaumann, Markus;  Wang, Ziyan;  Böhler, Esther;  Kemken, Dorit;  Kelm, Sørge;  Leibfritz, Dieter;  Azov, Vladimir A. 

New insights into the old reaction between acryloyl chlorides and pyridine
In: Tetrahedron letters. - Amsterdam [u.a.] : Elsevier Science, Bd. 56.2015, 9, S. 1124-1127Publikationslink   

2014

Artikel in Kongressband
Köhn, Claudia;  Trantzschel, Thomas;  Plaumann, Markus;  Bommerich, Ute;  Lego, Denise;  Bernarding, Johannes 

Field dependency of parahydrogen induced hyperpolarization (PHIP) of 1H and 19F in earthʾs magnetic field
In: Joint annual meeting ISMRM-ESMRMB. - Milan, S. 2784, 2014Publikationslink   

Plaumann, Markus;  Trantzschel, Thomas;  Lego, Denise;  Köhn, Claudia;  Sauer, Grit;  Gutmann, Torsten;  Bargon, Joachim;  Buntkowsky, Gerd;  Bommerich, Ute;  Bernarding, Johannes 

Hyperpolarization of a bisfluorinated phenylalanine derivative using PHIP and examination of the interaction with [beta]-cyclodextrin
In: Joint annual meeting ISMRM-ESMRMB. - Milan, S. 2780, 2014Publikationslink   

Plaumann, Markus 

PHIP hyperpolarization of fluorine: applications, examples and problems
In: European Network for Hyperpolarization Physics and Methodology in NMR and MRI, Zürich, 2014, 48

Plaumann, Markus;  Lego, Denise;  Trantzschel, Thomas;  Sauer, Grit;  Gutmann, Torsten;  Buntkowsky, Gerd;  Bargon, Joachim;  Bernarding, Johannes;  Bommerich, Ute 

19F NMR spectroscopy for the study of molecular interactions
In: GDCh – FGMR, Berlin, 2014, P60

Plaumann, Markus;  Lego, Denise;  Trantzschel, Thomas;  Wüstemann, Jan;  Sauer, Grit;  Gutmann, Torsten;  Buntkowsky, Gerd;  Bargon, Joachim;  Bernarding, Johannes;  Bommerich, Ute 

19F-Kernspinhyperpolarisation linearer und verzweigter Alkane
In: German Chapter of ISMRM, Jena, 2014

Trantzschel, Thomas;  Lego, Denise;  Plaumann, Markus;  Sauer, Grit;  Gutmann, Torsten;  Bargon, Joachim;  Buntkowsky, Gerd;  Bernarding, Johannes;  Bommerich, Ute 

PHIP of valproic acid and related structures
In: Joint annual meeting ISMRM-ESMRMB. - Milan, S. 2781, 2014Publikationslink   

Begutachteter Zeitschriftenartikel
Buntkowsky, Gerd;  Gutmann, Torsten;  Petrova, Marina V.;  Ivanov, Konstantin L.;  Bommerich, Ute;  Plaumann, Markus;  Bernarding, Johannes 

Dipolar induced para-hydrogen-induced polarization
In: Solid state nuclear magnetic resonance: an international journal - Orlando, Fla: Academic Press, Bd. 63/64.2014, S. 20-29; http://dx.doi.org/10.1016/j.ssnmr.2014.07.002

Lego, Denise;  Plaumann, Markus;  Trantzschel, Thomas;  Bargon, Joachim;  Scheich, Henning;  Buntkowsky, Gerd;  Gutmann, Torsten;  Sauer, Grit;  Bernarding, Johannes;  Bommerich, Ute 

Parahydrogen-induced polarization of carboxylic acids: a pilot study of valproic acid and related structures
In: NMR in biomedicine. - New York, NY : Wiley, Bd. 27.2014, 7, S. 810-816Publikationslink   

Warneke, Jonas;  Wang, Ziyan;  Zeller, Matthias;  Leibfritz, Dieter;  Plaumann, Markus;  Azov, Vladimir A. 

Methacryloyl chloride dimers - from structure elucidation to a manifold of chemical transformations
In: Tetrahedron: the international journal for the rapid publication of full original research papers and critical reviews in organic chemistry - Amsterdam [u.a.]: Elsevier Science, Bd. 70.2014, 37, S. 6515-6521; http://dx.doi.org/10.1016/j.tet.2014.07.019

2013

Artikel in Kongressband
Plaumann, Markus;  Trantzschel, Thomas;  Lego, Denise;  Köhn, Claudia;  Sauer, Grit;  Gutmann, Torsten;  Bargon, Joachim;  Buntkowsky, Gerd;  Bernarding, Johannes;  Bommerich, Ute 

Hyperpolarisation langkettiger Alkene mittels PHIP
In: German Chapter of ISMRM, ISSN 1863-6365, Freiburg (Deutschland), 2013, page 81

Plaumann, Markus;  Bommerich, Ute;  Trantzschel, Thomas;  Lego, Denise;  Dillenberger, Sonja;  Bargon, Joachim;  Buntkowsky, Gerd;  Bernarding, Johannes 

Hyperpolarization of biologically relevant compounds which are important in the GABA metabolism
In: Discovery, innovation & application - advancing mr for improved health , S. 3927, 2013Publikationslink   

Plaumann, Markus;  Trantzschel, Thomas;  Lego, Denise;  Sauer, Grit;  Gutmann, Torsten;  Bargon, Joachim;  Buntkowsky, Gerd;  Bernarding, Johannes;  Bommerich, Ute 

Hyperpolarized Fluorinated Amino Acid as NMR-based Biomarker
In: ESMRMB 2013, #471, Toulouse (Frankreich)

Begutachteter Zeitschriftenartikel
Plaumann, Markus;  Bommerich, Ute;  Trantzschel, Thomas;  Lego, Denise;  Dillenberger, Sonja;  Sauer, Grit;  Bargon, Joachim;  Buntkowsky, Gerd;  Bernarding, Johannes 

Parahydrogen-induced polarization transfer to 19F in perfluorocarbons for 19F NMR spectroscopy and MRI
In: Chemistry - a European journal. - Weinheim : Wiley-VCH, Bd. 19.2013, 20, S. 6334-6339Publikationslink   

Trantzschel, Thomas;  Plaumann, Markus;  Bernarding, Johannes;  Lego, Denise;  Ratajczyk, Tomasz;  Dillenberger, Sonja;  Buntkowsky, Gerd;  Bargon, Joachim;  Bommerich, Ute 

Application of parahydrogen-induced polarization to unprotected dehydroamino carboxylic acids
In: Applied magnetic resonance. - Wien [u.a] : Springer, Bd. 44.2013, 1/2, S. 267-278Publikationslink   

Buchbeitrag
Lützkendorf, Ralf;  Hertel, Frank;  Heidemann, Robin;  Thiel, Andreas;  Luchtmann, Michael;  Plaumann, Markus;  Stadler, Jörg;  Baecke, Sebastian;  Bernarding, Johannes 

Non-invasive high-resolution tracking of human neuronal pathways: diffusion tensor imaging at 7T with 1.2 mm isotropic voxel size
In: Medical imaging 2013. - Bellingham, Wash. : SPIE, insges. 7 S. - (Proceedings of SPIE; 8668)Publikationslink   

2012

Artikel in Kongressband
Plaumann, Markus;  Bernarding, Johannes;  Lego, Denise;  Trantzschel, Thomas;  Köhn, Claudia;  Dillenberger, Sonja;  Gutmann, Torsten;  Ratajczyk, Tomasz;  Bargon, Joachim;  Buntkowsky, Gerd;  Bommerich, Ute 

New strategy to hyperpolarize biological relevant molecules containing free amino-groups
In: ESMRMB, Lissabon, 2012, S.60, #222

Trantzschel, Thomas;  Plaumann, Markus;  Bernarding, Johannes;  Lego, Denise;  Ratajczyk, Tomasz;  Dillenberger, Sonja;  Buntkowsky, Gerd;  Bargon, Joachim;  Bommerich, Ute;  Bernarding, Johannes 

PHIP hyperpolarized ethanol - overcoming keto-enol tautomerism
In: ESMRMB, Lissabon, 2012, S.60, #224

Trantzschel, Thomas;  Bommerich, Ute;  Plaumann, Markus;  Lego, Denise;  Gutmann, Torsten;  Ratajczyk, Tomasz;  Dillenberger, Sonja;  Buntkowsky, Gerd;  Bargon, Joachim;  Bernarding, Johannes 

Synthesis of hyperpolarized Ethanol via PHIP
In: Adapting MR in a changing world, S. 1678, 2012Publikationslink   

Originalartikel in begutachteter internationaler Zeitschrift
Trantzschel, Thomas;  Bernarding, Johannes;  Plaumann, Markus;  Lego, Denise;  Gutmann, Torsten;  Ratajczyk, Tomasz;  Dillenberger, Sonja;  Buntkowsky, Gerd;  Bargon, Joachim;  Bommerich, Ute 

Parahydrogen induced polarization in face of keto-enol tautomerism: proof of concept with hyperpolarized ethanol
In: Physical chemistry, chemical physics. - Cambridge : The Royal Soc. of Chemistry, Bd. 14.2012, 16, S. 5601-5604Publikationslink   

2011

Artikel in Kongressband
Thomas Trantzschel;  Ute Bommerich;  Markus Plaumann;  Denise Lego;  Tomasz Ratajczyk;  Torsten Gutmann;  Sonja Dillenberger;  Gerd Buntkowsky;  Joachim Bargon;  Johannes Bernarding 

Biocompatible 19F Hyperpolarized Semifluorinated alkanes generated via PHIP
In: ESMRMB, Leipzig,2011, S.106, #520

Ute Bommerich;  Markus Plaumann;  Denise Lego;  Thomas Trantzschel;  Johannes Bernarding 

Generating 19F Hyperpolarized Semifluorinated alkanes via Parahydrogen-Transfer
In: SCM, Noordwijk,2011, #06

Ute Bommerich;  Markus Plaumann;  Thomas Trantzschel;  Joachim Bargon;  Gerd Buntkowsky;  Johannes Bernarding 

19F Hyperpolarization of Biocompatible Substrates Generated via Parahydrogen-Transfer
In: ISMRM, Montreal, 2011, #1521, S.179

Dissertation
Plaumann, Markus 

Synthese und Charakterisierung paramagnetischer Kontrastmittel für die molekulare Bildgebung
In: Shaker Verlag, Aachen, 2011

Originalartikel in begutachteter zeitschriftenartiger Reihe
Bommerich, Ute;  Trantzschel, Thomas;  Bargon, Joachim;  Buntkowsky, Gerd;  Bernarding, Johannes 

First step to 19F hyperpolarization of biocompatible substrates generated via parahydrogen-transfer
In: 19th annual ISMRM scientific meeting and exhibition 2011 ; Vol. 2. - Red Hook, NY : Curran, S. 1521Publikationslink   

2010

Artikel in Kongressband
Plaumann, Markus;  Ekkehard Küstermann;  Dieter Leibfritz 

Bis(Gd3+-GlyMe-DOTA)-Contrast Agent for 19F-Molecular MR Imaging at 7T
In: WMIC, Kyoto, 2010, #P0937B

Plaumann, Markus;  Dieter Leibfritz 

Fluorinated contrast agents with cation depending T1 sensitivity
In: Joint Meeting of ISMRM and ESMRMB, Stockholm, 2010, #4225

2009

Artikel in Kongressband
Plaumann, Markus;  Mireille Bipoun;  Dieter Leibfritz 

Comparison of different fluorinated AspGlyMe-DOTA- and GluGlyMe-DOTA-Gd-complexes
In: WMIC, Montreal, 2009, #619

Plaumann, Markus;  Ekkehard Küstermann;  Dieter Leibfritz 

New fluorinated Gd-AspGlyMe-DOTA complexes for 19F-MRI
In: ISMRM, Honolulu, 2009, #898

Plaumann, Markus;  Yvonne Neumann;  Dieter Leibfritz 

Novel lipophilic fluorinated TPP-Gd-contrast agents
In: ESMRMB, Antalya, 2009, #464

Plaumann, Markus;  Jan Willmann;  Dieter Leibfritz 

Observation of H/D-exchanges using ESI-MS
In: IMSC, Bremen, 2009, #222

Plaumann, Markus;  Dieter Leibfritz 

Synthesis of an isotope labelled Gd-complex
In: WMIC, Montreal, 2009, #620

2008

Artikel in Kongressband
Plaumann, Markus;  Jan Willmann;  Dieter Leibfritz 

Influence of temperature, pH, metalion and ligand system of the 19F-chemical shifts of fluorinated contrast agents
In: ESMRMB, Valencia, 2008, #587

Plaumann, Markus;  Jan Willmann;  Ekkehard Küstermann;  Uwe Schüssler;  Dieter Leibfritz 

Rat glioma C6 cells labeled with a fluorinated Gd-GlyMe-DOTA-complex
In: ISMRM, Toronto, 2008, #1693

Plaumann, Markus;  Jan Willmann;  Dieter Leibfritz 

Untersuchung lipophiler Eigenschaften von M3+-Kontrastmitteln mittels HPLC-ESI-MS
In: DGMS, Gießen, 2008, POr69

2007

Artikel in Kongressband
Plaumann, Markus;  Willmann, Jan;  Leibfritz, Dieter 

Charakterisierung Gd3+-haltiger Kontrastmittel mittels HPLC-ESI-MS
In: DGMS, Bremen, 2007, # 22

Plaumann, Markus;  Jan Willmann, Dieter Leibfritz 

Estimation of lipophilicity of complexes with different lanthanide(III) ions
In: SMI, Providence, 2007, #938

Plaumann, Markus;  Jan Willmann;  Dieter Leibfritz 

Synthesis and characterisation of fluorinated acyclic and macrocyclic Gd3+-complexes
In: SMI, Providence, 2007, #937

2006

Artikel in Kongressband
Markus Plaumann;  Jan Willmann;  Timo Dansauer;  Dieter Leibfritz 

Synthesis, characterisation and comparison of 3,5-bistrifluoromethyl substituted phenyl Gd-DTPA- and Gd-DOTA- complexes for 19F-molecular imaging
In: ISFC, Bremen, 2006, # ORG_101

Plaumann, Markus;  Willmann, Jan;  Dansauer, Timo;  Küstermann, Ekkehard;  Leibfritz Dieter 

Synthesis and comparison of fluorinated Gd-DTPA- and Gd-DOTA-Contrast agents for 19F-molecular imaging
In: ESMRMB, Warschau, 2006, # 535

2005

Artikel in Kongressband
Timo Dansauer;  Markus Plaumann;  Dorit Kemken;  Ekkehard Küstermann;  Dieter Leibfritz 

Fluorinated Gd-DTPA-Contrast Agents for 19F-Molecular MR Imaging
In: SMI, 2005, Köln, # 367

Profil

Forschung
Organische Synthese

  • Synthese fluorierter ungesättigter Verbindungen
  • Synthese von fluorierten Pyridiniumionen


Komplex-/Koordinationschemie und Katalyse

  • Synthese und Charakterisierung verschiedener metallorganischer Verbindungen
  • Untersuchung von Hydriermechanismen an ungesättigten organischen Verbindungen


NMR-Spektroskopie

  • Analyse biologischer Proben mittels NMR mittels der 1D- und 2D-NMR Spektroskopie
  • NMR-spektroskopische Stukturaufklärung von organischen und metal-organischen Verbindungen
  • NMR-spektroskopische Analyse der Bildung von Gast-Wirtkomplexen im Bereich der Medizinischen Chemie
  • Kernspinhyperpolarisation (PHIP, SABRE & photo-CIDNP)
  • Untersuchung des Polarisationstranfer von Wasserstoff auf Heterokerne (speziell 19F)


MR-Bildgebung

  • MR-Untersuchungen von neuen potentiellen 19F-Kontrastmitteln


Zellkultur

  • Zellmarkierung
  • Vitalitätsüberprüfungen


Lehre

  • Medizinische Informatik (Medizinische Fakultät, OvGU Magdeburg)
  • Medizinische Chemie (Universität Bremen)
  • Strukturaufklärung Organischer Verbindungen (Universität Bremen)
Service
  • Aufnahme NMR-spektroskopischer Daten an einem Bruker WB300 Ultrashield

 

    • Messungen mit 10mm Probenkopf (mit Gradient)
    • Kerne: 1H, 13C, 19F, 31P (weitere möglich)
    • 2D-NMR Spektren: HH-COSY, HSQC, HMBC (weitere möglich)
    • Auswertung 1D- und 2D-NMR Spektren zur Analyse bzw. Strukturaufklärung

 

  • Vitalitätsstudien/Zellkultur

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